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A man’s mother whas been discovered to have an advanced-stage brain tumor that needs immediate removal, with John Krasinski playing the role of bored office worker and would-be graphic novel author John Hollar, who moved to New York and is currently awaiting the birth of a baby with his well-to-do girlfriend, Becca. He receives a call to return to his Midwest home to be there for his mother Sally’s risky but crucial brain surgery, where he is greeted by his financially struggling plumber father, Don, and his recently laid-off brother Ron, who hasn’t yet been able to move on from his divorce.